WHAT IS XEOMIN®?

Xeomin, or incobotulinumtoxinA, is used on adults to improve the appearance of moderate to severe frown lines between the eyebrows. This prescription medication is temporary and contains a protein that is purified from the bacterium Clostridium botulinum, also known as botulinum toxin type A.

 

HOW DOES XEOMIN® WORK?

Any time that a person squints or frowns, the skin between their brows furrows and folds, which overtime causes persistent frown lines. These lines are caused when the skin loses some of its elasticity, which naturally occurs over time.  The active ingredient in XEOMIN®, Botulinum toxin type A, goes to work on the nerve endings in your muscles to prevent the contraction of the muscle fibers.  XEOMIN® temporarily reduces these lines on your forehead once these contractions are reduced.

 

IS XEOMIN® PROVEN?

In two separate clinical trials where 547 adult patients underwent randomized, double-blind, multicenter, placebo-controlled testing, XEOMIN® was proven to be effective. Out of these adults, the average age of the patients was 46 years. After receiving 20 units of XEOMIN®, patients were considered responders if the results were labeled as a 2-grade improvement. The improvements were based off of a 4 point scale that involved the assessment of both the physician and the patient.  Maintaining the same criteria, the success rate of the XEOMIN® patients was higher than those who received a placebo on Day 30. In both studies the success rates were 60% vs. 0% and 48% vs. 0%. The FDA approved XEOMIN® for aesthetic use in 2011 based on these two trials.

 

HOW DO I KNOW IF XEOMIN® IS RIGHT FOR ME?

Any adult who has moderate to severe glaellar lines (frown lines) can be classified as a candidate for XEOMIN®.  During your consultation with Our Aesthetic Team, it is important to discuss the benefits and risks of XEOMIN®. XEOMIN® cannot be taken if you are allergic to botulinum toxin or any of the ingredients in XEOMIN® or if you have had an allergic reaction in the past to any other botulinum toxin product or if you have had a skin infection at the intended injection site.

 

WHAT SHOULD I TELL MY DOCTOR BEFORE TREATMENT?

Before being treated with XEOMIN®, it is important to tell Our Team all medical conditions in your health history, including any diseases that have affected your muscles or nerves. Also tell him if you have had an allergic reaction to any botulinum toxin product, or any side affects you may have experienced from any other botulinum toxin previously.  Be sure to inform Our Aesthetic Team of all medications you are currently taking, including prescription and nonprescription medicines, herbal supplements and vitamins. In addition, be sure to inform Our Team if you have had any botulinum toxin product in the last four months, or in the past. It is important to inform us of exactly which product or products you received and the date in which you received them. FOR A COMPLETE DISCUSSION OF THE RISKS AND BENEFITS OF XEOMIN®, PLEASE SEE THE ACCOMPANYING XEOMIN MEDICATIONS GUIDE AND FULL PERSCRIBING INFORMATION GUIDE.

 

WHAT CAN I EXPECT DURING TREATMENT?

The treatment usually takes about 10-20 minutes, where Our Aesthetics Team will inject XEOMIN® into the muscles located in your forehead which are the cause of the your frown lines. This treatment does not require anesthesia, but a topical anesthetic or cold pack might be used to reduce any discomfort had.

 

WHEN CAN I EXPECT TO SEE RESULTS?

As early as 3-4 days after treatment, some patients have observed visible smoothing during the clinical trials. The maximum effect will typically occur at 30 days; however the median first onset of effect was recorded at less than a week.

 

WHAT ARE THE POSSIBLE SIDE EFFECTS OF XEOMIN®?

After treatment, it is possible for XEOMIN® to cause serious side effects, including allergic reactions. Allergic reaction symptoms to XEOMIN® can include: itching, rash, redness, swelling, wheezing, asthma symptoms, or dizziness/feeling faint. Contact our office or seek medical help immediately if you begin wheezing, experience other asthma symptoms, or if you feel faint or dizzy. When XEOMIN® was used in the clinical trials for the treatment of frown lines between the eyebrows, the most common side effect was headache.

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